The most popular cosmetic treatment in the world, hands down? Botox. Year over year, for two decades running, botulinum toxins have topped the nonsurgical charts, repeatedly proving their vast appeal across demographics.

“There are many reasons an undesired result can occur from neurotoxin treatment,” says Washington, D.C., board-certified dermatologist Dr. Noëlle Sherber. And not every flub is instantly fixable. “When there’s still [muscle] movement remaining after a toxin treatment, then some adjustment can be made by injecting additional units in precise anatomic areas, to counterbalance the existing result,” Dr. Sherber says. “But if the muscles are quite frozen, then often the best approach is to give the results time to fade.”

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